대학원생 구두발표(코스맥스)
[OC-1]
우수논문발표상 응모자Click-chemistry-derived triazole chitosan as a platform emulsifier for cosmeceuticals: Emulsion stability, RSM optimization, and biofunctional performance
발표자김수현 (건국대학교)
연구책임자고준석 (건국대학교)
Abstract
Oil in water emulsion in cosmetics require long-term stability, yet conventional surfactants may raise irritation and sustainability concerns. Chitosan(CS) is biocompatible and film-forming, but pH-dependent solubility and weak amphiphilicity often limit emulsification to acidic media. A triazole–phenyl moiety was grafted onto CS via CuAAC click chemistry to increase hydrophobicity and expand the stable formulation space for O/W emulsions. Native and modified formulations were evaluated by droplet-size(D4,3) and creaming index. For quantitative formulation analysis, RSM was used to model the combined effects of pH, oil fraction, and emulsifier concentration. Beyond physical stabilization, the platform was explored for cosmeceutical functionality. Future work will incorporate model actives to examine encapsulation, storage stability, and controlled release under skin-relevant conditions.