[3PS-126]
Adhesive and Conductive Hydrogel Fibrous Bandages for Enhanced Peripheral Nerve Regeneration
발표자진수빈 (성균관대학교)
연구책임자신미경 (성균관대학교)
Abstract
Peripheral nerve injury often causes motor and sensory impairments. While guidance conduits support axonal growth, mimicking tissue properties remains challenging. Here, we present a conductive, adhesive nerve bandage using a phenylborate-tethered hydrogel to enhance conductive polymer doping. Comprising electrospun hyaluronic acid microfibers coated with in situ polymerized polypyrrole, the bandage utilizes phenylborate groups for high pyrrole adsorption. This ensures tissue-like stretchability and adhesiveness without cracking. In a rat crush model, the sutureless bandage promoted regeneration by restoring electrical transmission, enabling functional recovery and preventing muscle atrophy. This bandage offers a promising platform for nerve repair and biomedical device integration.