Abstract
Most biomaterial surfaces lack inherent functionality, necessitating additional modification steps that are often restricted by the substrate material. To date, universal surface functionalization has been largely limited to specific methods like catechol-based polydopamine coatings. Herein, we report a facile, one-step surface modification strategy employing a boronic acid-functionalized polyacrylate. By incorporating butyl groups to lower the glass transition temperature (Tg), the polymer achieves robust interfacial adhesion across diverse substrates, including polymers, metals, and ceramics. This approach successfully imparts boronic acid functionality to these surfaces. Considering the versatility of boronic acid in biomedical engineering, this methodology holds significant potential for advancing the development of antifouling surfaces, biosensors, and bioadhesives.