[3PS-120]
Microfluidic Sweat Patch Integrated Smartwatch for Non-Invasive Photonic Continuous Glucose Monitoring
발표자정선아 (포항공과대학교)
연구책임자한세광 (포항공과대학교)
Abstract
Managing diabetes requires continuous glucose monitoring (CGM) to maintain homeostasis. To overcome the limitations of invasive blood sampling and unstable sweat collection in wearable sensors, we introduce a photonic sweat glucose sensor integrated with a Tesla valve-based microfluidic system. This geometry ensures continuous, evaporation-free, and unidirectional sweat flow with minimal backflow, facilitating stable acquisition. The sensing mechanism employs a glucose-responsive hydrogel matrix embedding glucose oxidase and an oxygen-sensitive phosphorescent dye. Using a smartwatch’s green LED for excitation, glucose levels are determined by analyzing fluorescence intensity changes. In vitro experiments validated a detection range of 0.01 mM to 1 mM. Furthermore, human trials demonstrated a strong correlation between sweat and blood glucose levels. This study shows the feasibility of integrating functional hydrogels with microfluidics for non-invasive wearable CGM.