Osteosarcoma remains difficult to treat due to recurrence, irregular bone defects, and insufficient vascularization, creating a need for multifunctional scaffolds that integrate therapy and regeneration. A bioinspired theragenerative platform was developed using 4D-printed shape memory polymer(SMP) scaffolds with synthetic adhesive-DNA(aDNA) immobilization. Inspired by sundew, the system embodies three levels of mimicry: motion mimicry through NIR-triggered shape recovery enabling minimally invasive implantation, surface mimicry via aDNA immobilization providing stable adhesion, and functional mimicry through aDNA-derived bioactivities with therapeutic reactions by near-infrared (NIR) irradiation. aDNA immobilization enhanced osteogenic differentiation, angiogenic activity, antioxidative effects, and immunomodulation. Under NIR irradiation, thermal modulation enabled tissue regeneration and tumor ablation with high density as a multifunctional theragenerative platform.