Highly photostable polymeric nanoparticle containing organic near-infrared dye with enhanced biocompatibility under hyperthermal irradiation
발표자
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초록
내용
Polymeric micelles are versatile nanocarriers to carry hydrophobic molecules within the core in aqueous media. Here we report engineered polymeric micelles encapsulating highly photostable organic near-infrared (NIR) dye, IR788, for generating heat under NIR irradiation. In addition, the core of micelle is stabilized via semi-interpenetrating network formation (sIPN), which exhibits highly enhanced photostable characteristics, ensures more stable loading environment under low temperature, and enhances biocompatibility in vitro compared to commonly used photothermal agent such as indocyanine green.