Exosomes in cancer immunotherapy: Implications as therapeutic targets and innate therapeutics
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초록
내용
The biological significance of exosomes as intercellular communication mediators has been increasingly revealed in a wide range of normal physiological processes and disease pathogenesis. In particular, regenerative and immunomodulatory exosomes hold potential as innate biotherapeutics, whereas pathological exosomes are considered therapeutic targets for inhibiting their bioactivity. In this presentation, the related previous work history, and initial accomplishments for regulating the in vivo fate of exosomes for cancer immunotherapy will be covered, along with our ambitions for future developments in the field.