Hydrogel ink for 3D printing with high and tunable mechanical properties realized by salting out effect
발표자
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초록
내용
Direct ink writing (DIW) technique for hydrogels offers promising potential for biomedical applications, as it allows for easy and rapid imitation of the human body with high accuracy. However, the application scope has been limited due to the mechanical properties of DIW hydrogel ink, which have fallen short compared to actual biological tissues and organs. In this study, we present a straightforward method for producing DIW hydrogel ink with adjustable mechanical properties using the salting-out effect. We explored the gelation mechanism induced by salting out and identified the gelation conditions at room temperature. The developed hydrogel ink not only exhibits the necessary rheological properties but also displays a variable Young's modulus ranging from 0.193-1.072 MPa. Furthermore, several applications using blood vessels printed with the developed ink are represented.