Lyotropic Self-assembly of Chiral Amphiphilic Random Copolymers in Aqueous Media
발표자
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초록
내용
The presence of chirality in nature is evident. Many biological architectures such as, the α – helix of DNA and polypeptides indicate that the point chirality in the molecular level is transmitted and amplified in the supramolecular level. Nature usesd self-assembly as a primary tool in the chirality transfer process by utilizing hydrophobic, electrostatic, hydrogen bonding, and steric interactions to develop well-defined structures. Taking inspiration from natural systems in a synthetic way, here we explore how the point chirality in the monomer is transferred into on the self-assembly of amphiphilic random copolymers in aqueous media. We will synthesize a chiral monomer possessing a stereocenter in the hydrophobic side chain and incorporate into the polymer. Then self-assembling aggregates will be generated in the presence of additional chiral and achiral additives. Their structural characterization and supramolecular chirality shall be discussed compared to achiral systems.