Biodegradable poly(glycerol sebacate)-based adhesive with hemispherical concave cups on hexagonal architectures
발표자
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초록
내용
Among biodegradable materials, poly (glycerol sebacate) (PGS) can be applied to microarchitecture-based tissue adhesive, because it has biodegradable and bioresorbable characteristics, that can induce interfacial adhesion by controlling mechanical properties. Herein, we presented a tissue adhesive fabricated using PGS, which can maintain adhesion even on a wet surface by mimicking the toe pad of a frog. To implement bioinspired adhesive architectures, the particular criteria under which PGS can be patterned were presented using simple models based on the degree of esterification and interfacial energy difference. Based on our investigation, wet adhesion in the adhesive was achieved by replicating the hexagonal micro-channel and concave cup structures existing hierarchically on the toe pad of frogs. The adhesion of PGS ahesive was measured on various organ surfaces, resulting in a stable wet adhesion with clean attachment and biodegradability.