Hyaluronate-based multifunctional hydrogels for 3-D bioprinting
발표자
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초록
내용
Three-dimensional (3-D) bioprinting has received much attention to construct functional tissues and organs. 3-D printing can also produce a highly complex tissue construct with the desired cell type and density. Hydrogels have been widely used as bioink in 3-D bioprinting due to their structural similarity to the natural extracellular matrix. Herein, self-healing and stretchable hydrogel systems were designed and used as bioink for extrusion-based 3-D printing. Oxidized hyaluronate and hydrazide-modified hyaluronate were used as base materials to prepare hydrogels. Various characteristics including viscoelastic properties, cell viability, self-healing ability, and stretchability of hydrogels were investigated. This hydrogel system also demonstrated the potential as bioink in 3-D bioprinting.