Relaxation dynamics in complex coacervate core hydrogels
발표자
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초록
내용
Complex coacervate core hydrogels(C3Hs) are formed by mixing of ABA and A’BA’ triblock copolyelectrolytes(PEs), where A and A’ blocks contain oppositely charged groups and B block is hydrophilic. Because of injectability and tunability, C3Hs have been widely investigated in the field of drug delivery system. In this study, we investigate the relaxation dynamics of C3Hs using dynamics mechanical analysis. Triblock and diblock PEs functionalized for ammonium and sulfonate were synthesized using anionic ring-opening polymerization and post-polymerization modification, and C3Hs were prepared by a combination of the triblock and diblock PEs. Since the triblock PEs act as crosslinkers between the coacervate cores, the relaxation dynamics of C3Hs are predominantly controlled by the chain dynamics of the triblock PEs. The results are discussed in terms of current understanding of block copolymer hydrogel relaxation, and particular attention is paid to the issue of core block extraction.