PCL Siloxane/PEG Multiblock Copolymer for Shape Memory Recovery Materials for Biomedical Application
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초록
내용
Polycaprolactone (PCL) is a polymer material widely used in medical devices for in vivo insertion. However, it has the disadvantage of insufficient elasticity and limitations in structural recovery. In this study, a PCL-based multi-block copolymer was synthesized including a siloxane block unit, which has been used for a long time as a representative FDA-approved material, and poly(ethylene glycol) (PEG), which is a highly biocompatible polymer that is widely used in biomedical applications. Through the introduction of these low Tg blocks, and crosslinkable end groups, PCL-based elastomers were synthesized and excellent shape memory properties were confirmed after crosslinking. Synthesis, characterization, and mechanical properties were reported. The shape memory property of this promising material can be applied to various biomedical applications, in particular, stents and graft jackets for ligament reinforcement.