Wireless Smart Theranostic Contact Lens for the Treatment of Glaucoma
발표자
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초록
내용
Glaucoma is one of the most dangerous and irreversible eye disease that can cause vision loss. It is important to monitor intraocular pressure (IOP) and take appropriate drug treatments according to IOP conditions. However, it is still highly challenge to achieve simultaneously monitor IOP and deliver appropriate drug to glaucoma patients. Here, we present the highly integrated theranostic smart contact lens with wireless circuit, sensitive hollow gold nanowire (AuHNW) based IOP sensor and the flexible drug delivery system (DDS) for feedback medical care of glaucoma. The AuHNW based IOP sensor has high biocompatibility, chemical stability and sensitivity. Furthermore, the flexible DDS can controlled release timolol for IOP control by electrical signals. The theranostic smart contact lens can successfully control the IOP in vivo tests with glaucoma induced rabbits.