2D and 3D co-spatial compartmentalized patch to enhance the therapeutic efficacy of keratinocytes for wound closure
발표자
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초록
내용
Keratinocytes are frequently used for the biological and biomedical remodeling of damaged skin tissues. However, low cell viability, poor cell maintenance, and lack of paracrine factors hamper the therapeutic efficacy of keratinocytes for skin wound healing. Here, we report the fabrication of a 2D and 3D co-spatial compartmentalized patch (CSCP) for a microscale keratinocyte-engineering platform and a novel method for delivering keratinocytes to enhance wound closure compared to that achieved by the conventional keratinocyte delivery method.