Hydroxyapatite deposited Titanium Substrates coated with Polyelectrolyte multilayer coating for Improved Interfacial Adherence and Biocompatibility
발표자
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초록
내용
Due to the increased needs of medical implants, various surface modification strategies have been developed to promote biological activation of hydroxyapatite (HAp) coatings for titanium (Ti) implantation. Spin coated HAp on Ti substrate has been applied because of its cost-effectiveness, good control of coating thickness, and chemical composition. However, Ti implants coated with hydroxyapatite require high interfacial adherence between HAp and Ti substrate to avoid implant failure. To improve the adhesive properties, we developed polyelectrolyte multilayer coatings comprised of chitosan and alginic acid on a Ti substrate. We characterized the coatings by FTIR, SEM, XRD, and AFM, and studied cellular interaction to the modified Hap/Ti samples by using osteoblast cells.