Gold nanorod-graphene hybrid nanoparticle system for anticancer therapy
발표자
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초록
내용
Recently, graphene is one of the most attractive biomaterials because it is less toxic than other carbon allotropes such as fullerene and carbon nanotubes. In particular, reduced graphene oxide (rGO) is suitable as a photothermal agent due to its significant improvement in light-to-heat conversion efficiency. Although rGO has the advantage of increasing the absorption rate of near-infrared (NIR) regions to increase the efficiency of light-to-heat conversion, it is difficult to use in the body due to its low dispersibility in aqueous solutions. In this study, we modified the suface of rGO to improve its dispersibility, and confirmed the synergistic effects of photothermal/photodynamic therapy by combining photosensitizer. It also expected that diagnosis and treatment will be possible at the same time by incorporating imaging technology through photoacoustic effect of rGO.