Interpretation of Polydiacetylene Nanosome-based carriers: Internanosomal behaviors, Endocytosis and enhanced Fluorescence
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초록
내용
Polydiacetylene (PDA) is well-known for colorimetric and fluorescent sensing material used for bio molecule detection platform. Nevertheless, PDA nanosome has not yet been considerably interpretat into the living cells environment. The intercolloidal behaviors and stability of PDA nanosomes. In incubation tests with various neocortical metal ions, The PDA nanosome which phenolic lipid added is believed to contribute to the interliposomal bridging interaction. Localized Surface Plasmon Resonance (LSPR) is potentially useful for amplifying fluorescence of PDA nanosome. The low concentration of negative AuNPs were amplified PDA nanosomes fluorescence. Based on real-time cell imaging and cell viability assessment by the H-aggregated PDA nanosome with R6G, the most highly polymerized nanosomes were found to be less toxic to cells. Moreover, it was revealed that the R6G quenched nanosome complex dissociates at cell environment, the PDA nanosome penetrates into cells.