Effects of electron-beam irradiation and poly ethylene glycol (PEG) contents on porous polysaccharide based coating for interventional medical devices
발표자
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초록
내용
The hydrophilic polymer coating of interventional medical devices is one of the important surface treatment technologies that minimizes damage to the patient's body by increasing lubricity on the surface. Since medical grade polymers are mostly hydrophobic, they have poor adhesion with hydrophilic polymer coating layer. In this study, poly(ether block amide) (PEBAX), a thermoplastic elastomer, was coated with a O-carboxymethyl chitosan (CMC). In order to improve the interfacial adhesion, the PEBAX surface was modified with acrylic acid (AAc) by electron-beam induced graft polymerization. Based on the results of Grafting yield, IR spectrum, it was confirmed that AAc was successfully graft polymerized onto the PEBAX, thereby stably bonding the CMC layer to the substrate. Furthermore, we prepared a porous coating layer by adding PEG into the CMC coating solution. The effects of process variables on the surface hydrophilic property were investigated by measuring SEM, water contact angle.