Post-transplantation tracking of the pancreatic islets by magnetic resonance imaging using iron oxide nanoparticles loaded tissue-adhesive microparticles
발표자
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초록
내용
The visualization of islet post-transplantation is necessary to improve the clinical outcomes of cell therapy for type 1 diabetes treatments. However, long-term and precise tracking of islets is still challenging. To address this issue, we developed a novel labeling method to track the pancreatic islet transplantation using T2 contrast agent-loaded tissue-adhesive microparticles. The results reveal that conjugation of our particles could be a promising strategy to improve the visualization of pancreatic islets in clinical applications.