Smart Wearable Devices for Ubiquitous Healthcare Applications
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We developed smart contact lens and smart wearable devices for both continuous diabetic monitoring and diabetic retinopathy therapy. Smart contact lens could measure tear glucose levels as a non-invasive alternative to the conventional blood glucose tests and deliver drugs from gold coated reservoirs for the treatment of diabetic retinopathy. On the basis of these results, we also developed a smart wearable device for highly sensitive glucose monitoring in sweat for clinically feasible diabetic diagnosis. A blue-tooth system could send data wirelessly allowing patients to check their diabetic diagnosis results on the mobile phones. Furthermore, we developed a NIR light emitting contact lens for the diabetic diagnosis and the treatment of diabetic retinopathy based on photobiomodulation. The retinal vascular hyper-permeability induced by diabetic retinopathy in rabbits was reduced to the statistically significant level by simply wearing the NIR light emitting contact lens.