Preparation of PEGlated conjugated polymer nanoparticles
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초록
내용
On these days, the developing application of conjugated polymers have gradually admitted as a promising material in different aspects. Their versatile properties such as high brightness, high photostability, and low cytotoxicity have transformed them to become alternatively multifunctional biomaterials. However, these organic-based materials were limited by the lack of hydrophilicity and bioavailability. This obstacle can be overcome by the incorporation of conjugated polymer nanoparticles (CPNs) to functionalized polyethylene glycol (PEG) in an aqueous medium. This research provides a view of different techniques in the fabrication of structural PEGlated CPNs formed from the phase-separated thin film [1] in the incorporation of a conductive polymer and a phospholipid. The difference in PEG-linked methods results in the changing of assembled molecular structures, thus giving the significant effect on the near infrared absorption and photothermal properties for theranostic applications.