POS8-0851
Development of Slide-Ring Hydrogels Using Polymerizable Polyrotaxane Crosslinkers
Topic
S8. Frontiers of Functional Polymers in Biology and Medicine
When and Where
Oct 1, 2026
08:30 - 09:30
Room 301 (Grand Ballroom)
Session Chairs
Jinkee HONG
Ki Su KIM
Presenter(s)
Seoyoung Han (Pusan National University)
Co-Author(s)
Abstract
Although hydrogels based on 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS) have been widely utilized due to their high water absorption capacity, their practical applications are often limited by insufficient mechanical strength. To address this issue, a nonionic hydrophilic comonomer, N,N′-dimethylacrylamide (DMAAm), was incorporated with AMPS via free radical copolymerization to construct the hydrogel network. In addition, a slide-ring hydrogel system was designed using polymerizable polyrotaxane (IEM-PRX) as a multifunctional crosslinker to introduce movable junctions within the network. The polyrotaxane was synthesized by threading α-cyclodextrin (α-CD) onto a poly(ethylene glycol) (PEG), followed by end-capping to prevent dethreading of α-CD from the PEG chain. 2-Isocyanatoethyl methacrylate (IEM) was grafted onto the threaded α-CD to introduce polymerizable groups. The resulting hydrogels were prepared to achieve enhanced mechanical properties while maintaining high swelling capability. Characterizations by NMR, FT-IR, DSC and TGA confirmed the chemical structure and properties of the synthesized materials.
