INS8-0652
Polyelectrolyte Thin Films and Hydrogel Composites for Adaptive Biosensing and Bone Tissue Engineering
Topic
S8. Frontiers of Functional Polymers in Biology and Medicine
When and Where
Sep 29, 2026
15:55 - 16:10
Room 108
Session Chairs
Sung Yun YANG
Kwangsoo SHIN
Presenter(s)
Sung Yun Yang (Chungnam Natl. Univ.)
Co-Author(s)
Abstract
Here we present multifunctional biomaterial platforms that integrate polyelectrolyte thin films with hydrogel-based composites to advance both bioelectronics and tissue engineering. Hydrogel-like polyelectrolyte coatings were engineered to modulate surface charge and hydrophilicity, enabling selective capture of nucleic acids and glucose. Cationic modifications on PCR platforms enhanced nucleic acid immobilization and amplification efficiency, while copper electrodes capped with polymeric layers facilitated Cu-ion-based non-enzymatic glucose sensing with more than twofold improvement in durability and sensitivity compared to uncoated electrodes. In addition, scaffold-hydrogel composites were designed to overcome poor adhesion between hydrophobic 3D-printed scaffolds and hydrophilic matrices. Natural polymer hydrogels, hydroxyapatite nanoparticles, and drug-carrying oligomers were integrated with functional surface coatings on ceramic, metal, and hydrogel substrates, resulting in improved interfacial adhesion, biocompatibility, and printability while supporting bone formation and regeneration. Together, these approaches demonstrate how interfacial engineering and functional hydrogel design converge to create adaptive, multifunctional biomaterials with broad potential in diagnostics, regenerative medicine, and therapeutic applications.
