ORGS2-0486
iCVD-deposited ultrathin adhesive copolymer film for tissue interfaces
Topic
GS2. Graduate Student Oral Session II: Functional Biomaterials and Cosmetic Polymer Engineering
When and Where
Sep 28, 2026
16:12 - 16:24
Room 102
Session Chairs
Chaenyung CHA
Ilkoo NOH
Jun Shik CHOI
Presenter(s)
Yunyoung Choi (KAIST/KIST)
Co-Author(s)
Abstract
Implantable bioelectronic devices require stable contact with biological tissues for reliable long-term operation. However, conventional tissue adhesives are typically based on bulk materials, limiting their integration with miniaturized devices. Ultrathin adhesive interfaces are therefore highly desirable, as reduced thickness minimizes the interfacial volume and better preserves device flexibility.
Herein, adhesive copolymer thin films composed of acrylic acid (AA) and pentafluorophenyl methacrylate (PFMA) were synthesized via initiated chemical vapor deposition (iCVD). The solvent-free vapor-phase process enabled conformal nanoscale coatings. AA provides hydrogen-bonding interactions, while PFMA offers reactive pentafluorophenyl ester groups capable of covalent bonding with tissue amines.
FTIR analysis confirmed successful copolymerization while preserving the functional groups of both monomers, and XPS analysis verified covalent bond formation between the PFMA ester groups and amine-containing substrates. Adhesion tests on model substrates and biological tissues showed that interfacial adhesion could be systematically tuned by copolymer composition, with PFMA content governing covalent contributions to tissue adhesion.
Herein, adhesive copolymer thin films composed of acrylic acid (AA) and pentafluorophenyl methacrylate (PFMA) were synthesized via initiated chemical vapor deposition (iCVD). The solvent-free vapor-phase process enabled conformal nanoscale coatings. AA provides hydrogen-bonding interactions, while PFMA offers reactive pentafluorophenyl ester groups capable of covalent bonding with tissue amines.
FTIR analysis confirmed successful copolymerization while preserving the functional groups of both monomers, and XPS analysis verified covalent bond formation between the PFMA ester groups and amine-containing substrates. Adhesion tests on model substrates and biological tissues showed that interfacial adhesion could be systematically tuned by copolymer composition, with PFMA content governing covalent contributions to tissue adhesion.
