POS1-1588
Hexadecimal Digital Information Storage via Sequence-Defined Polymers Synthesized by Passerini Iterative Exponential Growth (P-IEG)
Topic
S1. Polymer Synthesis
When and Where
Sep 29, 2026
08:30 - 09:30
Room 301 (Grand Ballroom)
Session Chairs
Hae Jung SON
Boseok KANG
Presenter(s)
Jeongyun Choi (Department of Chemistry, Seoul National University, Seoul, South Korea)
Co-Author(s)
Abstract
Sequence-defined polymers (SDPs) have emerged as a promising medium for ultra-high-density molecular data storage. Although recent advances have demonstrated the storage of binary and octal codes using continuous-flow chemistry and Passerini iterative exponential growth (P-IEG), achieving higher-order data density remains a significant challenge due to the limited variety of available monomers.
Herein, we report an advanced P-IEG strategy that enables hexadecimal digital information storage in uniform SDPs. By combining four distinct isocyanides and four different chain lengths, we established a library of sixteen chemically distinct monomers, where each monomer corresponds to a hexadecimal character ('0' to 'F'). Utilizing the combinatorial efficiency of the Passerini three-component reaction, we achieved rapid exponential chain growth with absolute sequence precision.
To demonstrate this method, a multicolored digital image was encoded by converting its hexadecimal color codes directly into the polymer sequences. This strategy significantly enhances the data storage capacity compared to conventional binary systems, offering a powerful methodology for next-generation, high-density molecular data storage.
Herein, we report an advanced P-IEG strategy that enables hexadecimal digital information storage in uniform SDPs. By combining four distinct isocyanides and four different chain lengths, we established a library of sixteen chemically distinct monomers, where each monomer corresponds to a hexadecimal character ('0' to 'F'). Utilizing the combinatorial efficiency of the Passerini three-component reaction, we achieved rapid exponential chain growth with absolute sequence precision.
To demonstrate this method, a multicolored digital image was encoded by converting its hexadecimal color codes directly into the polymer sequences. This strategy significantly enhances the data storage capacity compared to conventional binary systems, offering a powerful methodology for next-generation, high-density molecular data storage.
