POS3-0087
Biodegradable Porous Scaffold Platform via Green Solvent Processing of P3HP/PLA Blends
When and Where
Nov 30, -0001
12:00am - 12:00am
Presenter(s)
Seungho Baik (Kyung Hee University)
Co-Author(s)
Abstract
Sustainable materials processing is increasingly important for developing biodegradable polymer platforms with reduced environmental impact and reliable functionality. Porous scaffold systems require fabrication strategies that avoid toxic organic solvents while enabling control over structure, water accessibility, and post-fabrication functionality. Herein, we report a Cyrene-mediated green processing strategy for P3HP/PLA blend-based porous scaffolds. Cyrene, a lignocellulose-derived green solvent, enabled temperature-dependent gelation and thermally induced phase separation of the blends, followed by solvent exchange to form composition-dependent porous architectures. P3HP served as the primary biodegradable matrix, while PLA was incorporated to modulate structural integrity, pore architecture, and mechanical stability. The resulting scaffolds exhibited tunable morphology, water-accessible pore networks, and enhanced water infiltration/storage behavior. These structural features further enabled internal surface functionalization and cargo loading, supporting their potential as sustained-release platforms. Residual solvent and leachate assessments indicated effective Cyrene removal and ecological compatibility. This study highlights Cyrene-mediated P3HP/PLA blend processing as a sustainable route to biodegradable porous scaffold platforms with controlled architecture and functional applicability.
