POS4-1458
Selective Growth of ZIF-8 on Block Copolymer-Templated Au Nanodot Arrays as a Hybrid Platform for Reproducible SERS Sensing
Topic
S4. Colloids, Interfaces, and Molecular Assemblies for Functional Soft Materials
When and Where
Sep 29, 2026
08:30 - 09:30
Room 301 (Grand Ballroom)
Session Chairs
Hae Jung SON
Boseok KANG
Presenter(s)
SEUNGMIN KIM (Chungnam national university)
Co-Author(s)
Abstract
Achieving high reproducibility, selective target enrichment, and dense electromagnetic hotspots simultaneously remains a persistent bottleneck in developing practical Surface-Enhanced Raman Scattering (SERS) substrates. Conventional metallic nanostructures, while offering strong signal enhancement, often suffer from poor spot-to-spot uniformity and lack chemical selectivity, limiting real-world applicability.
To address this, we report a highly ordered hybrid SERS platform fabricated by selectively growing Zeolitic Imidazolate Framework-8 (ZIF-8) onto periodic Au nanodot arrays. Instead of conventional top-down lithography, we leveraged self-assembled cylindrical block copolymer (BCP) nanostructures as a large-area template to fabricate uniform Au nanodot arrays with high-density plasmonic hotspots, enabling scalable, cost-effective fabrication.
To interface the Au surface with the MOF phase, nanodots were pre-functionalized with carboxyl- or hydroxyl-terminated self-assembled monolayers (SAMs). These functional groups served as localized nucleation sites, coordinating with Zn²⁺ ions to selectively direct ZIF-8 shell growth precisely over the metallic nanodots. The resulting Au@ZIF-8 hybrid architecture couples the molecular sieving and enrichment capability of the porous MOF with the strong localized surface plasmon resonance (LSPR) of the underlying Au array.
SERS evaluations using probe molecules confirmed marked signal enhancement, outstanding spot-to-spot uniformity, and distinct chemical selectivity governed by the pore size of ZIF-8, enabling preferential enrichment of smaller target molecules while excluding larger interfering species. This approach offers a highly reproducible and reliable pathway toward advanced optical sensors tailored for complex chemical and biological monitoring.
To address this, we report a highly ordered hybrid SERS platform fabricated by selectively growing Zeolitic Imidazolate Framework-8 (ZIF-8) onto periodic Au nanodot arrays. Instead of conventional top-down lithography, we leveraged self-assembled cylindrical block copolymer (BCP) nanostructures as a large-area template to fabricate uniform Au nanodot arrays with high-density plasmonic hotspots, enabling scalable, cost-effective fabrication.
To interface the Au surface with the MOF phase, nanodots were pre-functionalized with carboxyl- or hydroxyl-terminated self-assembled monolayers (SAMs). These functional groups served as localized nucleation sites, coordinating with Zn²⁺ ions to selectively direct ZIF-8 shell growth precisely over the metallic nanodots. The resulting Au@ZIF-8 hybrid architecture couples the molecular sieving and enrichment capability of the porous MOF with the strong localized surface plasmon resonance (LSPR) of the underlying Au array.
SERS evaluations using probe molecules confirmed marked signal enhancement, outstanding spot-to-spot uniformity, and distinct chemical selectivity governed by the pore size of ZIF-8, enabling preferential enrichment of smaller target molecules while excluding larger interfering species. This approach offers a highly reproducible and reliable pathway toward advanced optical sensors tailored for complex chemical and biological monitoring.
