POS8-1289

Network Control of Gelatin–Carboxymethyl Cellulose–Chitosan Bioinks for Extrusion Bioprinting

Topic

S8. Frontiers of Functional Polymers in Biology and Medicine

When and Where

Oct 1, 2026 08:30 - 09:30

Room 301 (Grand Ballroom)

Session Chairs

Jinkee HONG

Ki Su KIM

Presenter(s)

Sunggeun Lee (Seoul National university of science and technology)

Co-Author(s)

Amitava Bhattacharyya (Seoul National university of science and technology), Ankita Mahji (Seoul National University of Science and Technology), Misook Kim (Seoul National university of science and technology), Andrea Justin Omelia Lyder (Seoul National university of science and technology), Iram Fatima (Seoul National University of Science and Technology), Oscar Manuel Benavides Bastidas (Seoul National University of Science and Technology), Insup Noh (Seoul National university of science and technology), Saleha Akter (Seoul National University of Science and Technology)

Abstract

Using digitally driven biomixing with the Biowork Pen®, self-crosslinked hydrogels were prepared from gelatin, carboxymethyl cellulose, and chitosan. An oxidized formulation introducing covalent crosslinking demonstrated superior printability and structural fidelity over the physically crosslinked alternative. This advanced covalent network effectively halved both swelling and degradation rates, enabling the reliable construction of a 120-layer, 2.9 cm tall tissue scaffold. Biological assays confirmed excellent cytocompatibility and accelerated wound closure, showcasing the platform's potential for complex, stable multilayer bioprinting and tissue engineering.

Acknowledgement: This work was financially supported by the Seoul National University of Science and Technology, Republic of Korea.

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