MXene-polyurethane composite scaffold for rotator cuff tendon repair and augmentation
발표자
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초록
내용
For a tendon repair, complex combinations of factors such as stimulation, healing factors, growth factors, and signaling substances are required. For high level of tendon augmentation, the methods such as suturing or attaching a composite scaffold to the tear area have been proposed. Polyurethane (PU) is widely used as a support biomaterial with nontoxicity. Also, it has been reported that electrical conductivity has a positive effect on tissue regeneration. Among conductive materials, MXene has high electrical conductivity and hydrophilicity. In this study, a composite film scaffold of MXene/PU was fabricated and applied to rotator cuff tendon repair. Cell proliferation, collagen synthesis, and mechanical properties were enhanced with increasing the amount of MXene. MXene appears to be a promising material for tendon tear healing. This work was supported by Korea Institute for Advancement of Technology (KIAT) grant funded by the MOTIE (P0017002, HRD Program for Industrial Innovation).