Gold Nanoparticle Conjugated BSA Nano-Dots Decorated Poly-Lysine Interface for the Selective Voltammetry Detection of Melatonin
발표자
()
초록
내용
Attributed to the compromised charge transfer of Protein-derived nanomaterials, their beneficial traits as an extraordinarily selective and specific bio-recognition element for the electrochemical sensors haven’t been fully exploited. Here in this work, we report a facile approach to electrochemically fabricate a BSA Nanodots conjugated AuNP, poly-Lysine biointerface for the voltammetric estimation of Melatonin. Using bovine serum albumin, quantum dots decorated with active functional groups were derived and further tailored with AuNP-poly Lysine to achieve the facilitated charge transfer and specific interactions with Melatonin. After detailed morphological and chemical characterization of the fabricated surface, its ability to estimate Melatonin was probed in a linear concentration range of 0.1–200 µM. Interface demonstrated a LOD of 31.6 nM without any substantial interference of Uric acid, Ascorbic acid, and Hypoxanthine.