Detection of a Nerve Agent Mimic based on Turbidity
발표자
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초록
내용
Nerve agents, toxic organophosphorus compounds used in chemical warfare, cause central nervous system paralysis by blocking the ability of acetylcholinesterase to break down the neurotransmitter acetylcholine. Despite the establishment of Organization for the Prohibition of Chemical Weapons (OPCW) in 1997, nerve agents continue to pose threat to public health and security due to their ease of production and maintenance. The need for rapid and visual detection methods that do not rely on extensive instrumentation has led to the development of a wide range of colorimetric and fluorescent probes. In this poster, we present a turbidity-based approach to detect nerve agent mimics using polymers that transform from water-insoluble to water-soluble in the presence of a nerve agent mimic. The results provide a different visual method for the detection of nerve agents in solution that rely on changes in light transmission rather than changes in color and/or absorption wavelengths.