Enhancing wound healing by tuning the mechanical properties of lignin/zwitterionic polymer-based multifunctional hydrogels
발표자
()
초록
내용
Tissue adhesives have attracted widespread interest as alternatives to sutures, but significant challenges remain, including weak tissue adhesion, inadequate biocompatibility, and uncontrolled biodegradation. We developed an adhesive lignogel with excellent cohesion and adhesion abilities through cation-pi interactions between the biopolymer lignin and a zwitterionic polymer. Lignogel was prepared by irradiating microwaves to an aqueous solution of lignin and zwitterionic polymers. The obtained gel showed various viscoelastic properties and electrical conductivity depending on the composition concentration. As the concentration increased, toughness increased, but surface adhesion decreased. Therefore, different concentrations of lignogel were mixed to ensure strong adhesion to biological tissues and thus accelerate wound healing. In this presentation, we introduce the synthesis strategy of lignogel, its characteristics, and biological applications.