Super-adaptive Bioinspired Non-invasive Adhesive Patches for Skincare
발표자
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초록
내용
Soft Structural Adhesive have become important to address the issues of human interactions for biomedical transdermal delivery. Drug delivery through complex skin is currently being studied using various innovative structural and material strategies due to the low delivery efficiency of the multilayered stratum corneum as a barrier function. This work introduces the design, operation mechanism, and performance of noninvasive transdermal patch with suction chamber cluster mimicking octopus-limb capable of wet adhesion with enhanced adhesion hysteresis and physical stimulation. The d-SCC facilitates cupping-driven drug delivery through the skin with only finger pressure. Our device enables nanoscale deformation control of stratum corneum of the engaged skin, allowing for efficient transport of diverse drugs through the stratum corneum without causing skin discomfort.