A Bottom-Up Design of Functional Carbon Nanofibers to Reinforce 3D-Printed Cardiovascular Polymer Scaffolds
발표자
()
초록
내용
This presentation describes a molecular design of functional carbonaceous nanofibers that reinforce 3D-printed cardiovascular polymer scaffolds. The additives were synthesized based on conjugated microporous polymers (CMPs), which are further carbonized to form functional carbon nanofibers. Of particular note is that thiophene units were embedded in the CMP precursors, which could promote the introduction of gold nanoparticles after carbonization. The Au-doped nanofibers not only reduced cytotoxicity but also improved the dispersibility of additives; so, they could form polymer composites facilely and further impart the desired functions to the resultant scaffolds. For example, with the addition of only 0.5 wt% of the additive in PCL, the 3D-printed functional cardiovascular scaffolds could be successfully prepared, which not only exhibit enhanced mechanical properties and cytocompatibilities but cause the controlled drug release triggerable by a NIR light.