Microfluidic system for easy monitoring of drug delivery and cytotoxicity
발표자
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초록
내용
Micro-fluidic system can be used in drug release study for monitoring of the drug concentration in micro-level, may provide more precise information about the efficacy of the drug. Here, we fabricated a micro-fluidic device for the study of an anticancer drug efficiency and toxicity with the drug-encapsulated hydrogel beads placed within a micro-channel of the device. We utilized layer-by-layer deposition method to modify the surface of the micro-channel of the device in order to prevent bio-fouling as well as provide the better cell culturing condition. The results of this study indicate that the microchannels suitably surface functionalized might be a available to effectively monitor cancerous cells upon the exposure to a anti-cancer drug encapsulated in micro-beads.