Development of anti-adhesion membrane using cartilage extracellular matrix.
발표자
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초록
내용
The extracellular matrix (ECM) is known to provide instructive cues for ultimately tissue regeneration. The ECM consists of specific functional molecules and not only provides essential supportive structure but also generates significant biological cues that are required for tissue repair. Numerous tissues and organs have now been decellularized for practical application of the ECM, and the latter has already been successfully used clinically. In particular, articular cartilage directly inhibited vessel formation in previous studies due to the anti-adhesive properties of the proteoglycan rich matrix. Porcine cartilage ECM membrane successfully fabricated to realize the functional anti-adhesion agent. The progress of development of ECM anti-adhesion membrane for clinical application will be shown from presentation.