Surface-tailored magnetic nanoparticles for direct and sensitive detection of glycoproteins
발표자
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초록
내용
Nanomaterials became important components in bioanalytical devices since they clearly enhance the performances in terms of sensitivity and detection limits down to single molecules detection. Magnetic nanoparticles (MNPs) have been intensively studied as biosensor materials due to their small size, biocompatibility and magnetic properties. MNPs can easily assembled by an external magnetic field, allowing more sensitive, faster, and accurate sensing of biomolecules. In addition, the MNPs have low background noise and strong electrical signals, so it can be analyzed without any signal conversion. In this study, we synthesized MNPs by co-precipitation method. The surface modification of MNPs was conducted using specific ligand for binding with biomolecules and enhancing solubility in water. Furthermore, the morphologies, chemical compositions and electromagnetic properties of MNPs were evaluated.