Fabrication of selectively reduced graphene oxide/gold nanorod composites for enhanced photothermal therapy
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초록
내용
Over the past few decades, various gold nanostructures have been demonstrated as a hyperthermia agent for photothermal therapy (PTT). Especially, gold nanorods (GNRs) have been studied intensively because of their simple synthetic method and excellent photothermal conversion efficiency compared to other gold nanostructures. However, GNRs are morphologically decomposed when exposed to heat for a long time, resulting poor photothermal effects. In this work, we prepared the GNRs combined with selectively reduced graphene oxide containing carboxyl groups (RGO-COOH) which can further improve the solubility and biocompatibility of GNRs. The physicochemical properties, morphologies and optical properties of RGO-COOH/GNR composites were determined. Their photothermal stabilities were also investigated upon exposure to near-infrared light irradiation.