Synthesis of Amphiphilic Goggle-shaped Multi-Block copolymer through Thiol-ene Click chemistry
발표자
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초록
내용
We present that 8-shaped polystyrene with di-thiol terminal (8-PS) can be used for the synthesis of multi-block copolymers (MBCPs) using thiol-ene click chemistry. The conventional synthetic method for MBCP such as living polymerization not only requires strict conditions but consider the combination of monomers. These limitations can be resolved with conjugation through click chemistry. By combining ATRP and click reaction we first synthesize disulfide containing tricycle polystyrene (TC-PS) which on reduction produce 8-PS. Similarly, a linear PS with di-thiol ends (l-PS) is also synthesized by ATRP. Then, we synthesize 2 types MBCPs: topologically goggle shaped multi-block copolymer (G-MBCP) and linear multi-block copolymer (L-MBCP) by conjugation of 8-PS and l-PS with di-norbornene PEG (di-NB-PEG). Raman spectroscopy and XPS are used to confirm the C-S as bridging bond in the formation of multi-block structures. Further, the MBCPs are characterized by SEC, 1H NMR, and MALDI-TOF MS.