DNA Binding Properties of DNA Block Copolymer Micelles
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We report the regulation of the molecular recognition properties of DNA block copolymer micelles with respect to the properties of polymer. Polymers of different type and length were coupled with DNA, and DNA block copolymers were self-assembled into spherical micelles having hydrophobic polymer segment as core, hydrophilic DNA as shell. DNA block copolymer micelles with different types of polymer exhibited different binding properties with complementary DNA. This presentation will discuss what affect the DNA binding properties of self-assembled DNA block copolymer assemblies.