Biodegradable Polymeric Nanoparticles as Contrast Agent for X-ray Computed Tomography Imaging
발표자
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초록
내용
In recent years, gold nanoparticles (AuNPs) were studied for computed tomography (CT) imaging contrast agents because of their high X-ray attenuation. However, gold nanoparticles cannot receive approval of FDA because of few side effects. Therefore, we made biodegradable polymer to use as CT contrast agent. Because high Z elements like iodine, gold, bismuth have high X-ray attenuation, this polymer have iodine can be used as CT contrast agent. In addition, this polymeric nanoparticles can be degradable in human body. For this study, it is expected to have X-ray high attenuation and ability of decomposition in human body.