Cryo-Preservative Hydrogel Combined with Dipole Interaction and Hydrogen Bonds
발표자
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초록
내용
Injectable hydrogel has been attracted great attention due to their ease of administration, porous structure, and similarity with extracellular matrix. However, to extend its application, several properties are required such as biocompatibility, antifouling property and cryo-preservative property during lyophilization. Thus, there have been many attempts to combine and maximize these properties . As one of these attempts, in our research we successfully synthesize triblock copolymer which can form 3D hydrogel in relatively low solid content by combining zwitterionic interaction and self-complementary quadruple hydrogen-bonding. Furthermore, we can examine that this block copolymer hydrogel shows dynamic self-adhesive, enhanced cryo-preservative, and antifouling property. We hope that our basic finding can be extended to actual usage in biological field such as a drug delivery system.