A promising diagnosis motif based on light signals derived from volumetric change of inverse opal hydrogels
발표자
()
초록
내용
Inverse opal hydrogels(IOHs) sensor have been drawing much attention due to their novel property. IOHs can swell in response to external stimuliation.Herein, we fabricated high quality biomarker responsive IOHs film. First, the array was prepared by self-assembly of monodisperse SNPs. Next, we backfilled the array with hydrogel precursor materials, followed by cross-linking using UV light. After removal of the SNPs array with hydrofluoric acid, we finally obtained macroporous IOHs.To summarize the results, we monitored the shift with controlling the pH and glucose concentration.The IOHs film responded to biomarkers through volume change with increased donnan potential. Increasing the pH and glucose concentration, the pore size of the IOHs was increased and color was changed. Based on optimized fabrication of IOHs above, our further research on development of biocompatible sensor for the detection of alzheimer related bio-functional signals would open new avenues in medical diagnosis.